Chromosomes 7 and 9 showed amplification of isoforms of the trypsin gene in the KMH2 (7q32.2-q36.3), L428 (7q34-q35) and DEL (7q11.1-q36.3) cell lines but not in SR-786 in the case of PRSS1/PRSS2, whereas PRSS3 showed amplification in HL cell lines (KMH2 at 9p21.1-p13.3 and L428 at 9p21.1-p12) but not in ALCL cell lines as shown in Figures 2 and 3. Here, PRSS2 is linked to anaplastic large cell lymphoma.