ACTB and hereditary elliptocytosis: In the PFC, a significant effect of Exploration was revealed on the BDNF mRNA levels normalized with β-actin [F(1,18) = 8.48; P < 0.01] that were higher in the LE group in the left hemisphere; there was no exploration × left/right hemisphere interaction in ANOVA and indeed a similar difference between the LE and HE groups in the right hemisphere which missed the conventional level of significance was also notable (Fig. 4).