Because the chronic exposure to the hepatotoxin CCl4 can induce liver cirrhosis in humans, and it is a classical method of inducing liver injury and fibrosis in mice [10], [16], we analyzed whether it induces liver cirrhosis in mice expressing the dominant negative, nonphosphorylatable RSK-inhibitory C/EBPβ-Ala217 transgene. This evidence concerns the gene CEBPB and cirrhosis of liver.