In a first screen, two parameters were checked: (a) the non-selective inhibition of COX-1/COX-2 enzyme activities, measured by the production of PGE2 in cultured mouse colon adenocarcinoma (CT26) and mouse Lewis lung carcinoma cells (D122) cells; (b) the M-channel activity, measured by the heterologous coexpression of Kv7.2 and Kv7.3 subunits in Chinese hamster ovary (CHO) cells. The gene discussed is KCNQ2; the disease is Carcinoma, Lewis Lung.