SERPINE1 and obesity due to melanocortin 4 receptor deficiency: It is interesting to note that PAI1 correlated significantly with all obesity variables (with BMI, 0.53; PBF, 0.51; WAIST, 0.56), IL6 (0.49), dyslipidemia, even with SBP and DBP, reaching almost the lowest but still significant correlation with fibrinogen (Table 2).