In addition, despite the undisputed usefulness of GFP fusion proteins, their expression was linked to changes in the physiological state of living cells such as induction of apoptosis [9], dilated cardiomyopathy in transgenic mice [10], impairment of actin-myosin interactions [11,12], inhibition of polyubiquitination [13], and cytokine induction [14]. The gene discussed is MYH14; the disease is dilated cardiomyopathy.