However, this mutation has not been found among Caucasians.8 Among Caucasians, Lp-PLA2 was reported to be an independent risk factor for CAD and stroke in many,9-14 but not all, studies.15-17 Data assessing the relationship of CAC with Lp-PLA2 are very limited among Caucasians18,19 and there are no data, to our knowledge, among the Japanese. The gene discussed is PLA2G7; the disease is stroke disorder.