This finding was in contrast to previous findings from the same population that showed Lp-PLA2 as a predictor of CHD and stroke.10 In the Coronary Artery Risk Development in Young Adults (CARDIA) study,18 however, Lp-PLA2 level had a significant and independent association with CAC among young white and black American men and women. The gene discussed is PLA2G7; the disease is Stroke.