MAP1LC3A and neoplasm: With a view to determine if an autophagic pathway or another cell death pathway had been activated in the tumour cells or not, we observed the localisation of LC3 after transient transfection (of MKN45 cells and AsPC-1 cells) of a plasmid encoding GFP-LC3 24 h after treatment with PM-8 or PM-17 (Figure 4B).