INI1 mutations have not been described in ependymomas (Sevenet et al, 1999a; Kraus et al, 2001; Weber et al, 2001), whereas biallelic inactivation of INI1 and loss of INI1 protein expression are characteristic features of AT/RTs (Versteege et al, 1998; Judkins et al, 2004; Biegel, 2006). The gene discussed is SMARCB1; the disease is ependymoma.