Indeed, POSTN gene was found to be overexpressed in various human cancers such as ovary [4,9], colon [6], pancreas [7,10], thyroid [11], oral squamous cell carcinoma [12,13], breast [5], lung [14] and neuroblastoma [15] and higher POSTN expression levels were correlated with increased tumor aggressiveness and/or poorer survival in NSLC [14,16], SCLC [17], neuroblastoma [15], colon cancers [6], thyroid carcinomas [11], oral squamous cell carcinoma [12] and pancreatic ductal adenocarcinoma [10]. Here, POSTN is linked to malignant colon neoplasm.