Annexin A1 has been reported to show altered expression in a variety of different cancers, including oesophageal cancer (Paweletz et al, 2000; Hu et al, 2004; Wang et al, 2006), pancreatic cancer (Bai et al, 2004) and hairy cell leukaemia (Falini et al, 2004). The gene discussed is ANXA1; the disease is familial pancreatic carcinoma.