The renal neoplastic cells failed to stain with antibodies against renal cell carcinoma marker (RCC) {Ventana} [Figure 3D], S-100 protein (Ventana), chromogranin (Ventana), cytokeratins (AE1/AE3, 8/18, 7/20) {Ventana}, CD34 (Ventana), and myogenin (Ventana) {not shown}. The gene discussed is MYOG; the disease is renal cell carcinoma.