In contrast to all other infections, 18sRNA was not an unreliable control gene when MDDCs were infected with HIV-1BaL. In addition it is of note that although GAPDH was one of the most reliable reference genes identified overall, it was the third most unreliable gene in HELA cells infected with HSV-1NC1(whereas it was the second most reliable reference gene in HEP2 cells infected with the same strain of HSV-1). This evidence concerns the gene GAPDH and infection.