A recent German study of 441 cases and 552 controls reported an increase in breast cancer risk associated with genetic variation in PRL: rs1341239 (SNP35) (OR, 1.67; 95%CI, 1.11–2.50 for homozygous individuals) and rs12210179 (OR, 2.09; 95%CI, 1.23–3.52), which we did not genotype in our sample. Here, PRL is linked to breast cancer.