During our analyses, we realized that dendritic cells expressing CD123, CD208, CD209, CD1a and Langerin do not seem to play a major role in the local immunology of human colorectal cancer, since the infiltration frequency of these CD123-positive plasmacytoid DC, DC positive for CD208 and CD209, and CD1a/Langerin-positive Langerhans cells is very low. The gene discussed is LAMP3; the disease is colorectal cancer.