TUBB3 and neoplasm: The transchromosomic tumours also showed an almost two fold reduction of mRNA for mouse Tubb3, a neuron specific gene (Fig. 1C; t-test, p = 0.007, paired t-test p = 0.111 but non-overlapping standard error bars), and a three-fold reduction of mouse Gfap mRNA, a glia specific gene (Fig. 1D; t-test, p = 0.00001, paired t-test p = 0.003).