RTN4R and schizophrenia: Previously, we provided weak evidence for an association between RTN4R variation and susceptibility to schizophrenia by identifying three distinct variants located at the 3′ end of the RTN4R gene that were preferentially transmitted in individuals with schizophrenia in two independent, family-based samples from the U.S. (N = 106 triads) and South Africa (N = 93 triads) [22].