We chose the 7 SNPs to be genotyped based upon those previously shown to be associated with AMD at the CFH gene locus: rs529825, rs3766404, rs1061147, rs800292, rs1061170, rs203674 and rs2274700.[4] A backward step-wise selection method and the FBAT were chosen because multi-SNP effects are allowed that are not additive. The gene discussed is CFH; the disease is age-related macular degeneration.