Accordingly, we found a significant decrease in the weight of the interaction between JAG1–IL4, IL10–IL12A, and IL12A–STAT6 in patients with MS (p<0.05), and a significant increase in the weight of the interaction between TGFB1–IL12A and PTPRC–JAG1 when compared to HC (p<0.05). This evidence concerns the gene IL12A and myeloid sarcoma.