HSPE1 and periodontitis: Subjects with periodontitis had markedly lower plasma concentrations of HSP10 (median difference 404.8 μg/ml, 95% CI 332.4–499.1, P<0.0001) and lower concentrations of BiP (median difference 417.9 μg/ml, 95% CI 336.8–503.3, P<0.05) when compared to controls.