CEACAM5 and neoplasm: Tumour size has never shown a clear prognostic value (Newland et al, 1994; Frank et al, 1995; Takahashi et al, 1997), but its potential effect has always been evaluated through overall survival analyses, in which it has shown a satisfying correlation with carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9) levels (Louhimo et al, 2002; Yuste et al, 2003).