MMP9 and pulmonary fibrosis: MMP-9 (gelatinase B) has been implicated in the pathogenesis of asthma (Cataldo et al. 2000), idiopathic pulmonary fibrosis (Fukuda et al. 1998), chronic obstructive pulmonary disease (COPD; Russell et al. 2002), and acute lung injury (Lanchou et al. 2003).