Very recently a survey of 76 ovarian cancer patients using Q-PCR detection of GPR54 and kisspeptin transcripts [35] demonstrated a negative correlation between KiSS-1 and GPR54 mRNA levels with residual disease, although they showed no correlation with histopathological subtype (possibly due to the relatively small number of clear cell ovarian cancers in that cohort), however the overall correlation observed in this study is in agreement with our observations. This evidence concerns the gene KISS1 and ovarian clear cell cancer.