A series of studies have shown that inhibitory effects of TZDs and AdPPARγ on both eosinophilia and AHR were prevented by GW9662 and implicate increases in phosphatase and tensin homologue deleted on chromosome ten (PTEN) and IL-10 in the protective roles of PPARγ-activation [36, 37, 47]. This evidence concerns the gene AHR and Increased total eosinophil count.