In the second case, patients usually have no underlying thyroid abnormalities, whereas a markedly increased serum interleukin 6 (IL-6) concentration, along with histopathologic findings demonstrating moderate to severe follicular damage, support the destructive nature of AIT type II, which seems to result from discharge of preformed thyroid hormones from disrupted follicles [3,8]. This evidence concerns the gene IL6 and thyroiditis.