SOD1 and neuroblastoma: Contrarily, there was no significant difference in the metabolic activity of NAC-treated and untreated Wt-SOD1 cells after pneumolysin incubation, i.e., NAC did not protect Wt-SOD1 neuroblastoma cells from the toxic action of pneumolysin (Fig. 9 &10) (56.9 ± 4.3% mitochondrial metabolic activity in pneumolysin-treated Wt-SOD1 cells versus 54.5 ± 6.6% in pneumolysin-exposed Wt-SOD1 cells with 72 hours pre-incubation with NAC, p > 0.05).