Chemokines are less well studied in severe malaria, but recent studies have associated severe malaria infection with increased production of chemokines of the C-C or β subfamily, including regulated upon activation, normal T cell expressed and secreted (RANTES), monocyte chemotactic protein (MCP)-1, macrophage inflammatory protein (MIP)-1α, MIP-1β, and IL-8 [2,13,26-28]. This evidence concerns the gene CCL5 and malaria.