In addition, the haplotype bifurcation plots centered on HLA-DRB1*0301 for UK SLE, CEPH, and Yoruba populations in Figure 3B illustrate preservation of the common HLA-DRB1*0301 haplotype in CEPH and UK SLE, while that seen in the Yoruba is significantly different. Here, HLA-DRB1 is linked to systemic lupus erythematosus.