Furthermore, closer inspection of these data reveals that microsatellite-inference of HLA-DRB1 alleles in the MN SLE dataset may underestimate the frequency of HLA-DRB1*0301 and overestimate that of HLA-DRB1*1501, thus diminishing the effect of the former and enhancing that of the latter. This evidence concerns the gene HLA-DRB1 and systemic lupus erythematosus.