CR2 and B-cell non-Hodgkin lymphoma: Previous reports suggest up to two-third of B-cell lymphomas express CD21, but little distinction was made between low and high expressors (Nadler et al, 1983; Scoazec et al, 1989; Gloghini & Carbone, 1993; Echeverri et al, 2002; Otsuka et al, 2004).