The frequency of MGMT methylation as detected by both techniques was different from most previous studies on cervical carcinomas, in which by MSP analysis MGMT methylation frequencies varying from 6.7 to 38% have been reported (Dong et al, 2001; Virmani et al, 2001; Yang et al, 2004; Lin et al, 2005). The gene discussed is MGMT; the disease is cervical carcinoma.