MGMT and lung cancer: The DNA repair gene, MGMT, frequently inactivated in brain, colorectal, lung, and lymphomas (Esteller et al, 1999a), and the potential metastasis inhibitor DAP-kinase gene altered in lymphomas, leukaemias, and lung cancer, were also reported with aberrant methylation (Katzenellenbogen et al, 1999; Esteller et al, 1999b).