Various other mechanisms explain how other factors like VEGF, PDGF and interleukins influence tumour growth (Dvorak, 1986; Dvorak et al, 1995; Abramovich et al, 1999; Balkwill and Mantovani, 2001; Coussens and Werb, 2002; Chang et al, 2005). The gene discussed is VEGFA; the disease is neoplasm.