Remarkably, nine of these 21 genes were significantly down-regulated in Lb17 attacked flies at the 21–24-h time point post-infection, four of which are thought to function in actin nucleation and branching as part of the Arp2/3 and SCAR complex (Abi, Arp2, kette, Sra-1). This evidence concerns the gene RPS4X and infection.