CXCL8 and coronary artery disorder: Data from previous studies have suggested that neutrophils in patients with stable CAD or in individuals at high risk for vascular events possess a primed character compared to neutrophils from healthy individuals, i.e. the cells are “hyperactive” ex vivo as assessed by increased chemotactic activity and increased production of ROS, LTB4 and IL-8 [6], [8], [9].