PTGS2 and colorectal carcinoma: The prostaglandin concentrations in the medium were in the Mv1Lu cells 64.9 pg ml−1 in controls and 157.7 pg ml−1 in the COX-2 transfected cells, whereas in the human CRC-line HCT-15, the mean concentration was 100 pg ml−1 in controls and 450 pg ml−1 in the COX-2-expressing cells.