BCL2L1 and neoplasm: Since tumor invasion and metastasis often involve modulation of the actin cytoskeleton to increase cell motility [27,28], we evaluated the actin cytoskeleton in tumors from RIP-Tag; RIP-tva mice infected with RCASBP-Bcl-xL, using an immunofluorescence assay with rhodamine-phalloidin to display filamentous actin (F-actin).