BCL2L1 and invasive carcinoma: We observed a dramatic rearrangement of the actin cytoskeleton in invasive carcinomas at 2 and 5 wk after infection with RCASBP-Bcl-xL, but not in tumors from age-matched animals infected with RCASBP-ALPP (Figure 7A), suggesting that Bcl-xL remodels the actin cytoskeleton to increase cell motility.