RIP-Tag; RIP-tva mice infected with RCASBP-Bcl-xL exhibited higher tumor burdens (for three ages p ≤ 0.009, Wilcoxon rank sum test) and a greater tumor incidence at all three ages (9, 12, and 16 wk of age) than did the bitransgenic control mice infected with RCASBP-ALPP (Figure 5B). Here, ALPP is linked to neoplasm.