NME2 and cancer: Given that EGCG has been shown to inhibit cancer-associated enzymes such as matrix metalloproteinases (MMPs) (Yamakawa et al, 2004) and the proteasome (Kazi et al, 2004), we suggest that EGCG and EA inhibition of secreted NDPK-B is another anticancer and antiangiogenic property that can be attributed to these polyphenolic compounds.