Tumour 24R3 has three nonsynonymous mutations in the gene PIK3CD. The tumour harbours 1p-deletion, but has two alleles at the site of the mutations according to DNA sequencing (see Figure 4), hence the deletion does not cover this region or more probably, the wild-type allele comes from contaminating normal cells in the DNA sample, indicated by single-nucleotide polymorphisms (SNP) array analysis carried out on the tumour (data not shown). Here, PIK3CD is linked to neoplasm.