MCM2 and ovarian adenocarcinoma: This concept is reinforced by the fact that higher MCM-2 and MCM-5 LIs were observed in the 32 (47.8% of cases) ovarian adenocarcinomas with p53 LI more than 10%, a cutoff that that has been shown to be efficient for the identification of p53 mutations in paraffin blocks staining (Banks et al, 1986).