A strong positive correlation was established between MCM-2 or MCM-5 expression level and Ki-67 LI (Spearman's rho=0.7214, P<0.0001 and rho=0.6449, P<0.0001, respectively), which remained after stratification of our cases into borderline (P<0.0001 and 0.0038, respectively) or carcinoma categories (P=0.0242 and <0.0001, respectively). This evidence concerns the gene MKI67 and carcinoma.