Six out of 8 animals (75%) in the NB8-E6 group, and 7/8 mice (88%) in the group engrafted with NB8-CXCR4-C3 developed a tumour, thus showing a similar tumour take in mice engrafted with CXCR4-negative or CXCR4 positive NB8 cell line (Figure 2a). The gene discussed is CXCR4; the disease is neoplasm.