As shown in figure 6c, at day 44, N91-pAB303 tumours were significantly larger (mean volume 703 mm3) than CXCR4 knocked-down N91-shCXCR4-CS1 and N91-shCXCR4-CS2 tumours (mean volume 74.8 mm3 and 9.7 mm3 respectively) (p<0.05 Mann Whitney test). Here, CXCR4 is linked to neoplasm.