BRF2 and breast cancer: In agreement with [6] we observed regions of recurrent high-level amplification on chromosomes 8, 11, 12, 17 and 20 (Figure 1a) bounding well-known breast cancer oncogenes (e.g. BRF2, ASH2L, CCND1, EMSY, ERBB2, NCOA3, MYBL2, STK6) [10,23,24], although amplification frequencies were much lower on chromosomes 12 and 20 as compared with those reported in [6].