The most 5' SNP, namely rs2562582, located within 2 kilobases from the initiation of the SLC1A3 transcript, exhibited initial evidence for association with MS (P = 0.005) in the transmission disequilibrium test (TDT) analysis, suggesting a possible functional role for this variant in the transcriptional regulation of this gene. The gene discussed is SLC1A3; the disease is myeloid sarcoma.