To find out, which of these receptors may be instrumental for autocrine effects of VEGF-C, we analysed their mRNA or protein expression in five human breast cancer cell lines (MCF-7, T-47D, SK-BR-3, Hs578T, and MDA-MB-231), which differ in their expression of COX-2 and VEGF-C (Timoshenko et al, 2006). The gene discussed is VEGFC; the disease is breast cancer.