Vascular endothelial growth factor (VEGF)-C is the major lymphangiogenic factor which is expressed in certain normal tissues, for example large intestinal and mammary duct epithelia, skeletal and cardiac muscle, thyroid, ovary, and prostate (Joory et al, 2006) as well as in a variety of cancerous tissues including breast cancer (Kinoshita et al, 2001; Nakamura et al, 2003, 2005, 2006). Here, VEGFC is linked to breast carcinoma.