However, altered glycosylation in cancer can play an important role in tumour cell adhesion and migration (Orntoft and Vestergaard, 1999), as well as in extravasation via interaction with galectin-3 on endothelial cells (Lehr and Pienta, 1998; Glinsky et al, 2000; Krishnan et al, 2005). Here, LGALS3 is linked to neoplasm.