Expression of RBM5 mRNA is downregulated in tumour tissue compared to normal tissue [11-16], although our recent study reports that expression of RBM5 mRNA is marginally upregulated (p = 0.063) and protein is significantly upregulated (p = 1.43 × 10-8) in breast tumour tissue [6]. Here, RBM5 is linked to breast neoplasm.