In the study described herein, we set out to investigate the existence of an RBM6-RBM5 chimeric transcript whose expression, or protein product, regulated expression of RBM6 and RBM5. Here we report the unexpected identification of not one but three novel non-coding RBM6-RBM5 chimeric mRNA transcripts, which were differentially expressed in tumour versus non-tumour tissue and whose expression was not associated with decreased RBM6 or RBM5 mRNA expression levels. Here, RBM5 is linked to neoplasm.