We found 7 SNPs in or near TCF7L2. One 100K SNP (rs7100927) was in moderate LD (r2 = 0.5) with TCF7L2-associated SNP rs7903146 and was nominally associated with a 56% increased relative risk of diabetes (p = 0.007) and with tFPG (GEE p = 0.03). Here, TCF7L2 is linked to diabetes mellitus.