Overexpression of SOD2 in deficient cell lines has reduced the proliferation of pancreatic carcinoma cells (Weydert et al, 2003; Ough et al, 2004), multiple myeloma cells (Hodge et al, 2005b), glioma cells (Zhong et al, 1997), squamous oral carcinoma cells (Liu et al, 1997), and prostate carcinoma cells (Li et al, 1998b; Zhong et al, 2004; Venkataraman et al, 2005). This evidence concerns the gene SOD2 and exocrine pancreatic carcinoma.