These characteristics included tumour margin, histological types and subtypes, tumour surrounding breast tissue type, tumour grade, mitotic index, tumour size, nuclear pleomorphism, stage of the disease, lymphocyte involvement, breast laterality, nature of surgical management (operation performed), and degree of expression of the prognostic markers Her-2, oestrogen receptor (ER), and progesterone receptor (PgR). The gene discussed is PGR; the disease is neoplasm.