SORBS3 and schizophrenia: SORBS3 (also known as vinexin, SCAM-1 or SH3D4), which encodes a cell adhesion molecule expressed in neurons and glia [28], becomes progressively more likely to be methylated with age, and is methylated to a greater degree in Alzheimer patients (median PMR = 38.5, N = 18) than in all other cases (schizophrenia, controls) older than 60 years (median PMR = 16.9, N = 39, P = 0.00081).