PTGS2 and infection: To confirm the role of COX-2 in vGPCR-induced PGE2 secretion, SC-560 (COX-1 selective inhibitor), NS-398 (COX-2 selective inhibitor), or Indomethacin (Non-selective COX inhibitor) was added to vGPCR-expressing HUVEC at 24 hours post-infection for a 24-hour treatment.